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Last Updated: 2024-03-22 (yyyy-mm-dd).

Title: EP4 receptor ep4 receptor com

Description: Prostaglandin receptor a sub relatives of mobile floor 7 transmembrane receptors are the G protein coupled receptors The EP4 prostaglandin receptor EP4R is a member of the 7 transmembrane receptor superfamily EP4 is one particular of 4 receptors identified for prostaglandin E2 PGE2 This receptor can activate T mobile issue signaling It has been proven to mediate PGE2 induced expression of early development reaction 1 EGR1 regulate the stage and balance of cyclooxygenase two mRNA and direct to the phosphorylation of glycogen synthase kinase 3 The EP4R gene spans somewhere around 22 kb and is composed of a few exons divided by two introns The initially exon 530 bp is noncoding Immediately after an intron of 472 bp the second exon is made up of a brief 43 bp 5 sequence prior to a 289 amino acid open reading through body ORF An 11 5 kb intron is identified at the conclude of transmembrane six and the rest of the ORF is in exon 3 The gene composition is analogous to those of the thromboxane PGI and PGD receptors

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Address: 2500 North State Street Jackson Mississippi 39216

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